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Everything about Respiratory Failure totally explained

Respiratory failure is a medical term for inadequate gas exchange by the respiratory system. Respiratory failure can be indicated by observing a drop in blood oxygen level (hypoxemia) and/or a rise in arterial carbon dioxide (hypercapnia) which can be written as (PaO2 < 60 mmHg, PaCO2 > 45 mmHg). Classification into type I or type II relates to the absence or presence of hypercapnia respectively. (Values in kPA being PO2 below 8kPA and PCO2 above 6.7kPa

Types

Type 1

Type 1 respiratory failure is defined as hypoxaemia without hypercapnia, indeed the CO2 level may be normal or low. It is typically caused by a ventilation/perfusion mismatch; the air flowing in and out of the lungs isn't matched with the flow of blood to the lungs.
   This type is caused by conditions that affect oxygenation like:
  • Parenchymal disease(V/Q mismatch)
  • Diseases of vasculature and shunts.

Type 2

Type 2 respiratory failure is defined as the build up of carbon dioxide that has been generated by the body. The underlying causes include:
  • Reduced breathing effort (in the fatigued patient)
  • Increased resistance to breathing (such as in asthma)
  • A decrease in the area of the lung available for gas exchange (such as in emphysema).

    Causes

  • Pulmonary dysfunction
  • Cardiac dysfunction
  • Other

    Treatment

    Emergency treatment follows the principles of cardiopulmonary resuscitation. Treatment of the underlying cause is required. Mechanical ventilation may be required.

    Further Information

    Get more info on 'Respiratory Failure'.


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